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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
12.42
Human Site:
S2691
Identified Species:
22.78
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
S2691
P
G
P
W
H
A
S
S
G
K
D
V
P
E
C
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
S2691
P
G
P
W
H
A
S
S
G
K
D
V
P
E
C
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
S2691
P
G
P
W
H
A
S
S
G
K
D
V
P
E
C
Dog
Lupus familis
XP_852631
1216
141588
T1207
I
E
V
T
L
L
G
T
S
K
E
I
K
C
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
L2464
T
D
L
C
Q
A
S
L
E
K
D
V
S
Q
C
Rat
Rattus norvegicus
Q7TSP2
1385
159522
N1376
T
E
K
L
R
A
E
N
V
F
L
K
E
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
K2141
K
W
F
E
T
S
E
K
D
R
V
S
D
C
N
Frog
Xenopus laevis
NP_001080954
2954
339950
S2917
P
S
Q
F
F
D
N
S
K
L
G
D
F
S
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
A2004
Q
Q
L
Q
L
C
G
A
E
F
Q
A
S
G
L
Honey Bee
Apis mellifera
XP_001121311
1418
164919
S1409
N
S
N
V
T
K
L
S
R
H
L
D
I
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
Y2507
R
R
A
G
Q
P
P
Y
Q
G
T
L
N
E
R
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
A1238
L
N
L
K
K
Q
I
A
A
L
T
G
Q
R
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
V1339
Q
V
V
T
Y
L
K
V
I
Q
P
F
T
V
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
100
100
6.6
N.A.
40
6.6
N.A.
N.A.
0
13.3
N.A.
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
46.6
13.3
N.A.
N.A.
13.3
26.6
N.A.
N.A.
6.6
6.6
N.A.
13.3
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
39
0
16
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
0
0
0
16
31
% C
% Asp:
0
8
0
0
0
8
0
0
8
0
31
16
8
0
0
% D
% Glu:
0
16
0
8
0
0
16
0
16
0
8
0
8
31
8
% E
% Phe:
0
0
8
8
8
0
0
0
0
16
0
8
8
0
0
% F
% Gly:
0
24
0
8
0
0
16
0
24
8
8
8
0
8
0
% G
% His:
0
0
0
0
24
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
8
0
0
8
8
0
0
% I
% Lys:
8
0
8
8
8
8
8
8
8
39
0
8
8
0
24
% K
% Leu:
8
0
24
8
16
16
8
8
0
16
16
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
0
0
0
8
8
0
0
0
0
8
0
8
% N
% Pro:
31
0
24
0
0
8
8
0
0
0
8
0
24
0
0
% P
% Gln:
16
8
8
8
16
8
0
0
8
8
8
0
8
8
0
% Q
% Arg:
8
8
0
0
8
0
0
0
8
8
0
0
0
24
8
% R
% Ser:
0
16
0
0
0
8
31
39
8
0
0
8
16
8
0
% S
% Thr:
16
0
0
16
16
0
0
8
0
0
16
0
8
0
16
% T
% Val:
0
8
16
8
0
0
0
8
8
0
8
31
0
8
0
% V
% Trp:
0
8
0
24
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _